Description

5-Chloro-4-Methylpyrimidine-2-Carbonitrile is a high-purity, versatile pyrimidine derivative that serves as a critical synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require a substituted pyrimidine core.
• Chemical Research & Development: Serves as a versatile precursor for further functionalization (e.g., Suzuki coupling, nucleophilic substitution) in academic and industrial R&D labs.
• Material Science: Potential intermediate in the development of organic electronic materials and ligands for catalytic systems.

Basic Information

Product Name	5-Chloro-4-Methylpyrimidine-2-Carbonitrile
CAS No.	114969-79-8
Molecular Formula	C6H4ClN3
Molecular Weight	153.57 g/mol
Synonyms	2-Cyano-5-chloro-4-methylpyrimidine; 4-Methyl-5-chloropyrimidine-2-carbonitrile; 5-Chloro-4-methyl-2-pyrimidinecarbonitrile; 5-Chloro-4-methylpyrimidine-2-carbonitrile; 2-Pyrimidinecarbonitrile, 5-chloro-4-methyl-
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-Methylpyrimidine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.