Description

Pyrimidine, 5-Chloro-, 1-Oxide (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key precursor for developing novel pharmaceuticals and agrochemicals, where its unique chlorinated N-oxide structure enables the creation of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the pyrimidine core is a common bioactive motif.
• Fine Chemical Manufacturing: Acts as a versatile building block for synthesizing complex organic molecules, dyes, and functional materials in custom synthesis and process chemistry.
• Academic & Industrial Research: Employed in chemical research for studying heterocyclic chemistry, reaction mechanisms, and developing new synthetic methodologies.
• Ligand and Catalyst Development: Potential use in the design of novel ligands for metal catalysis or as a component in organocatalysts due to its N-oxide functionality.

Basic Information

Product Name	Pyrimidine, 5-Chloro-, 1-Oxide (9Ci)
CAS No.	114969-48-1
Molecular Formula	C4H3ClN2O
Molecular Weight	130.53 g/mol
Synonyms	5-Chloropyrimidine 1-Oxide; 5-Chloropyrimidine N-Oxide; 5-Chloro-1-oxidopyrimidin-1-ium; 5-Chloropyrimidine-1-oxide; 1-Oxido-5-chloropyrimidin-1-ium; 5-Chloro-1-hydroxypyrimidine; 5-Chloropyrimidine-1-ol
EINECS	Contact for details

Quality Control

Our Pyrimidine, 5-Chloro-, 1-Oxide (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing specifications such as assay (by HPLC), impurity profile, and physical characteristics. We support cGMP and ISO-aligned practices for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.