Description

2-Chloro-4-Ethoxy-6-(Trifluoromethyl)Pyrimidine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is critical for research and development in the pharmaceutical and agrochemical sectors, where its unique pyrimidine core and trifluoromethyl group enable the creation of novel active ingredients. It is primarily sought after by R&D chemists and process development scientists working on new drug candidates, crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Serves as a crucial precursor for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Material Science Research: Used in the development of advanced organic materials, including liquid crystals, polymers, and electronic chemicals.
• Chemical Biology & Proteomics: Employed as a reactive handle or linker in the design of chemical probes and bioconjugates for target identification and validation.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	2-Chloro-4-Ethoxy-6-(Trifluoromethyl)Pyrimidine
CAS No.	114963-95-0
Molecular Formula	C7H6ClF3N2O
Molecular Weight	226.58 g/mol
Synonyms	2-Chloro-4-ethoxy-6-(trifluoromethyl)pyrimidine; 4-Ethoxy-2-chloro-6-(trifluoromethyl)pyrimidine; 6-(Trifluoromethyl)-2-chloro-4-ethoxypyrimidine; 2-Chloro-4-ethoxy-6-trifluoromethylpyrimidine; Pyrimidine, 2-chloro-4-ethoxy-6-(trifluoromethyl)-; 114963-95-0; 2-Chloro-4-ethoxy-6-trifluoromethyl-pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Ethoxy-6-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.