Description

Boc-L-3-Methylphe CAS NO 114873-06-2 is a protected amino acid derivative, specifically the tert-butoxycarbonyl (Boc) derivative of L-3-methylphenylalanine. This compound is a critical building block in solid-phase peptide synthesis (SPPS), where it serves to protect the amine functionality during chain assembly. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptide-based therapeutics, diagnostics, and biochemical tools. The high purity and consistent quality of this intermediate are essential for ensuring the success and reproducibility of complex peptide synthesis projects.

Application

• Peptide Synthesis: A fundamental protected amino acid for the stepwise construction of custom peptides in both research and GMP manufacturing settings.
• Pharmaceutical Intermediates: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) containing non-natural amino acid motifs.
• Bioconjugation: Used to introduce the 3-methylphenylalanine side chain into proteins or other biomolecules for structure-activity relationship (SAR) studies.
• Chemical Biology Research: Employed in the synthesis of peptide libraries for high-throughput screening and drug discovery campaigns.
• Agrochemical Development: Can be utilized in the design and synthesis of novel peptide-based crop protection agents.
• Material Science: Acts as a monomer for creating specialized polyamides or peptide-polymer hybrids with unique properties.

Basic Information

Product Name	Boc-L-3-Methylphe
CAS No.	114873-06-2
Molecular Formula	C₁₅H₂₁NO₄
Molecular Weight	279.33 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)-3-(3-methylphenyl)propanoic acid; Boc-3-methyl-L-phenylalanine; N-(tert-Butoxycarbonyl)-3-methyl-L-phenylalanine; Boc-L-3-Methylphenylalanine; N-Boc-3-methyl-L-phenylalanine; Boc-L-β-(3-Methylphenyl)alanine; tert-Butyloxycarbonyl-L-3-methylphenylalanine; L-3-Methylphenylalanine, N-Boc derivative
EINECS	Contact for details

Quality Control

Our Boc-L-3-Methylphe is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.5%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.