Description

4-Chloro-6-(1H-Imidazol-1-Yl)Pyrimidine is a high-value heterocyclic building block featuring a pyrimidine core substituted with both chloro and imidazolyl functional groups. This molecular architecture makes it a critical intermediate for the synthesis of more complex active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in kinase inhibitor and antiviral agent development.
• Agrochemical Synthesis: Used as a building block for creating advanced herbicides, fungicides, and insecticides with specific modes of action.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Preparation: The imidazole moiety can be utilized to create ligands for metal complexes used in catalytic processes.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Chloro-6-(1H-Imidazol-1-Yl)Pyrimidine
CAS No.	114834-02-5
Molecular Formula	C7H5ClN4
Molecular Weight	180.59 g/mol
Synonyms	4-Chloro-6-(imidazol-1-yl)pyrimidine; 6-(1H-Imidazol-1-yl)-4-chloropyrimidine; 4-Chloro-6-imidazol-1-yl-pyrimidine; 1-(4-Chloropyrimidin-6-yl)-1H-imidazole; 4-Chloro-6-(1H-imidazol-1-yl)pyrimidine; Pyrimidine, 4-chloro-6-(1H-imidazol-1-yl)-; 114834-02-5
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(1H-Imidazol-1-Yl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.