Description

4-Chloro-6-(1H-Pyrazol-1-Yl)Pyrimidine is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. Its core value lies in its bifunctional reactivity, serving as a key intermediate for constructing complex molecular architectures in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the life sciences sector for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its pyrimidine-pyrazole scaffold.
• Chemical Biology: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways.
• Material Science: Potential building block for the synthesis of specialty polymers and ligands for metal-organic frameworks (MOFs).
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	4-Chloro-6-(1H-Pyrazol-1-Yl)Pyrimidine
CAS No.	114833-95-3
Molecular Formula	C7H5ClN4
Molecular Weight	180.59 g/mol
Synonyms	4-Chloro-6-(1H-pyrazol-1-yl)pyrimidine; 4-Chloro-6-pyrazol-1-ylpyrimidine; 6-Chloro-4-(1H-pyrazol-1-yl)pyrimidine; 4-Chloro-6-(1-pyrazolyl)pyrimidine; Pyrimidine, 4-chloro-6-(1H-pyrazol-1-yl)-; 1-(4-Chloro-6-pyrimidinyl)-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(1H-Pyrazol-1-Yl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.