Description

3-Chlorodiaminopimelic Acid is a specialized, non-proteinogenic amino acid derivative that serves as a critical chiral building block and biochemical research tool. Its value lies in its unique structure, which incorporates both amino and carboxylic acid functional groups alongside a chlorine substituent, enabling its use in the synthesis of complex molecules and as a potential enzyme inhibitor. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors who require high-purity intermediates for drug discovery, peptide synthesis, and metabolic pathway studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in antibiotic and enzyme inhibitor programs.
• Biochemical Research: Used as a substrate analog or inhibitor in enzymatic studies, especially those related to lysine and diaminopimelate metabolism in bacteria and plants.
• Peptide Synthesis: Serves as a modified amino acid residue for introducing structural diversity and specific functional groups into synthetic peptides.
• Agrochemical Development: Employed in the synthesis of advanced crop protection agents and herbicides that target specific plant metabolic pathways.
• Microbiology & Nutrition: Investigated for its role in bacterial cell wall biosynthesis and as a component in specialized microbial growth media.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying protein-ligand interactions and cellular processes.

Basic Information

Product Name	3-Chlorodiaminopimelic Acid
CAS No.	114831-14-0
Molecular Formula	C7H13ClN2O4
Molecular Weight	224.64 g/mol
Synonyms	3-Chloro-DAP; (2R,6S)-2-Amino-3-chloro-6-[(1R)-1-aminoethyl]piperidine-2,6-dicarboxylic acid; 3-Chloro-2,6-diaminopimelic acid; 3-Cl-DAP; Chlorodiaminopimelate; 3-Chlorodiaminopimelate; 114831-14-0; 3-Chloro-2,6-diaminoheptanedioic acid
EINECS	Contact for details

Quality Control

Our 3-Chlorodiaminopimelic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment. We support cGMP and ISO 9001 compliant production for pharmaceutical customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.