Description

Triphosphoric Acid, p-[[(2S,5R)-5-[2-Amino-5-(3-Amino-1-Propyn-1-Yl)-1,4-Dihydro-4-Oxo-7H-Pyrrolo[2,3-D]Pyrimidin-7-Yl]Tetrahydro-2-Furanyl]Methyl] Ester is a sophisticated nucleoside analog derivative, representing a key building block in advanced pharmaceutical research and development. Its complex molecular structure is engineered to act as a potent inhibitor, making it a critical component for targeting specific enzymatic pathways. This high-purity intermediate is essential for researchers and manufacturers in the life sciences sector, particularly those focused on antiviral and anticancer therapeutic discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate mechanisms of action and drug resistance.
• Proteomics & Molecular Biology: Employed in the development of probes and tools for studying nucleic acid metabolism and related cellular processes.
• Preclinical Drug Development: Integral for formulating active pharmaceutical ingredients (APIs) during early-stage drug candidate optimization and efficacy testing.

Basic Information

Product Name	Triphosphoric Acid, p-[[(2S,5R)-5-[2-Amino-5-(3-Amino-1-Propyn-1-Yl)-1,4-Dihydro-4-Oxo-7H-Pyrrolo[2,3-D]Pyrimidin-7-Yl]Tetrahydro-2-Furanyl]Methyl] Ester
CAS No.	114748-61-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	7H-Pyrrolo[2,3-d]pyrimidin-7-yl Tetrahydrofuran Nucleoside Triphosphate Derivative; Amino-propyne Modified Nucleoside Ester; Nucleoside Triphosphate Analog; Antiviral Nucleoside Intermediate; (2S,5R)-Tetrahydrofuran Nucleotide Building Block; 2-Amino-7H-pyrrolo[2,3-d]pyrimidine Triphosphate Ester; Pro-drug Nucleotide Intermediate
EINECS	Contact for details

Quality Control

Our Triphosphoric Acid derivative is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically assessed via HPLC, NMR, and mass spectrometry. We adhere to cGMP guidelines where applicable to support our clients' regulatory and compliance needs in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, inert environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep desiccated under argon or nitrogen atmosphere. Allow the sealed container to reach room temperature before opening to minimize condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.