Description

L-Leucine Thioamide Hydrochloride is a high-purity, non-natural amino acid derivative with significant potential in advanced research and development. This compound serves as a critical synthetic intermediate and building block for the creation of novel peptides, enzyme inhibitors, and other bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on medicinal chemistry and proteomics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of peptide-based drugs and enzyme inhibitors targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of novel therapeutic candidates.
• Bioconjugation & Probe Development: Acts as a precursor for creating labeled probes or affinity tags used in biochemical assays and diagnostic research.
• Peptidomimetics: Integral in designing and synthesizing peptidomimetic compounds that mimic natural peptides with enhanced stability or activity.
• Academic & Institutional R&D: Employed in university and research institute laboratories for fundamental studies in organic synthesis and chemical biology.

Basic Information

Product Name	L-Leucine Thioamide Hydrochloride
CAS No.	114747-12-5
Molecular Formula	C7H15ClN2OS
Molecular Weight	210.72 g/mol
Synonyms	L-2-Amino-4-methylpentanethioamide hydrochloride; (S)-2-Amino-4-methylpentanethioamide hydrochloride; L-Leucinethioamide hydrochloride; H-Leu-thioamide·HCl; (2S)-2-Amino-4-methylpentanethioamide hydrochloride; Leucine thioamide HCl; L-Leu-thioamide hydrochloride
EINECS	Contact for details

Quality Control

Our L-Leucine Thioamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.