Description

Ac-D-Met(O)-Oh CAS NO 114714-85-1 is a high-purity, protected amino acid derivative, specifically the N-acetylated form of D-methionine sulfoxide. This compound is a critical chiral building block and intermediate in advanced organic synthesis, particularly in the pharmaceutical and biotechnology sectors. It is essential for researchers and manufacturers developing peptide-based therapeutics, diagnostic agents, and novel bioactive molecules where precise stereochemistry and side-chain modification are required.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel peptide drugs and enzyme inhibitors.
• Peptide Synthesis: Used in Solid-Phase Peptide Synthesis (SPPS) and solution-phase methods to incorporate oxidized methionine residues into peptide sequences.
• Biochemical Research: Serves as a standard or reagent in studies of protein oxidation, redox biology, and methionine sulfoxide reductase systems.
• Proteomics & Diagnostics: Can be utilized in the synthesis of labeled peptides for mass spectrometry and diagnostic assay development.
• Academic & Industrial R&D: A valuable tool for chemists and biologists exploring structure-activity relationships (SAR) and new chemical entities.

Basic Information

Product Name	Ac-D-Met(O)-Oh
CAS No.	114714-85-1
Molecular Formula	C7H13NO4S
Molecular Weight	207.25 g/mol
Synonyms	N-Acetyl-D-methionine sulfoxide; N-Acetyl-D-methionine S-oxide; Ac-D-Met(O)-OH; (R)-2-Acetamido-4-(methylsulfinyl)butanoic acid; D-Methionine sulfoxide, N-acetyl-; N-Acetyl-D-methionine sulfoxide; N-Ac-D-Met(O)-OH
EINECS	Contact for details

Quality Control

Every batch of Ac-D-Met(O)-Oh is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and optical rotation analysis, to ensure high chemical and chiral purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.