Description

4-(2-Chloro-5H-Pyrrolo[3,2-D]Pyrimidin-4-Yl)Morpholine is a high-purity heterocyclic organic compound featuring a fused pyrrolopyrimidine core, which is a privileged scaffold in medicinal chemistry. This molecule serves as a critical advanced pharmaceutical intermediate (API) for the synthesis of targeted kinase inhibitors. It is essential for research and development teams in the pharmaceutical and biotechnology sectors focused on oncology and inflammatory disease therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drugs, particularly kinase inhibitors.
• Oncology Research: Used in the development of targeted cancer therapies that interfere with specific signaling pathways.
• Biochemical Tool Compound: Serves as a precursor or reference standard in assay development and high-throughput screening.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Academic & Contract Research: Utilized in university and CRO laboratories for exploratory medicinal chemistry and structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-(2-Chloro-5H-Pyrrolo[3,2-D]Pyrimidin-4-Yl)Morpholine
CAS No.	114684-96-7
Molecular Formula	C10H11ClN4O
Molecular Weight	238.67 g/mol
Synonyms	4-(2-Chloro-5H-pyrrolo[3,2-d]pyrimidin-4-yl)morpholine; 2-Chloro-4-morpholino-5H-pyrrolo[3,2-d]pyrimidine; 4-Morpholino-2-chloro-5H-pyrrolo[3,2-d]pyrimidine; 2-Chloro-4-(4-morpholinyl)-5H-pyrrolo[3,2-d]pyrimidine; CAS 114684-96-7
EINECS	Contact for details

Quality Control

Our production of 4-(2-Chloro-5H-Pyrrolo[3,2-D]Pyrimidin-4-Yl)Morpholine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.