Description

Lhrh, Phe(5)-δ-Ala(6)-n-Et-Pronh2(9)- CAS NO 114681-52-6 is a synthetic peptide analog of Gonadotropin-Releasing Hormone (GnRH), engineered with specific amino acid modifications to enhance its stability and receptor binding profile. This compound is critical for advanced research and development in endocrinology and reproductive medicine, offering a valuable tool for studying hormonal regulation pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutic agents and diagnostic assays.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in the development of novel GnRH-based therapeutics.
• Endocrinology Studies: Used in in vitro and in vivo research to investigate the hypothalamic-pituitary-gonadal axis, receptor-ligand interactions, and signal transduction mechanisms.
• Biochemical Assay Development: Employed as a critical component in the development and validation of high-throughput screening (HTS) assays and diagnostic kits.
• Preclinical Studies: Utilized in animal model research to evaluate the efficacy, pharmacokinetics, and pharmacodynamics of potential peptide drugs.
• Peptide Chemistry & Synthesis: Acts as an intermediate or a finished compound for studying structure-activity relationships (SAR) in peptide analog design.

Basic Information

Product Name	Lhrh, Phe(5)-δ-Ala(6)-n-Et-Pronh2(9)- CAS NO 114681-52-6
CAS No.	114681-52-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GnRH Analog; Luteinizing Hormone-Releasing Hormone Analog; [Des-Gly10, D-Ala6, Pro-NHEt9]-GnRH; Gonadorelin Analog; LHRH (5-Phe, 6-D-Ala, 9-N-Et-Pro-NH2); Peptide LHRH Agonist/Antagonist; 114681-52-6; Synthetic GnRH Peptide
EINECS	Contact for details

Quality Control

Our Lhrh, Phe(5)-δ-Ala(6)-n-Et-Pronh2(9)- CAS NO 114681-52-6 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and stringent controls for residual solvents and related substances. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure full traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This hygroscopic (moisture-sensitive) material should be handled under a dry, inert atmosphere to prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.