Description

Lhrh, Phe(5)-δ-Ala(6)- is a synthetic peptide analog of Luteinizing Hormone-Releasing Hormone (LHRH), characterized by a specific modification at the sixth amino acid position. This structural alteration is designed to enhance metabolic stability and receptor binding affinity, making it a critical intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in the fields of endocrinology, oncology, and reproductive medicine.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel LHRH analogs and antagonists.
• Endocrine Disorder Studies: Used in preclinical research to investigate hormone regulation pathways and potential treatments for conditions like prostate cancer, breast cancer, and endometriosis.
• Peptide Chemistry: Acts as a building block for medicinal chemists to create new peptide-based drug candidates with improved pharmacokinetic profiles.
• Biochemical Assays: Employed as a ligand in receptor binding studies and other in vitro assays to understand hormone-receptor interactions.
• Academic Research: Utilized in university and institutional labs for fundamental studies in peptide science and molecular biology.

Basic Information

Product Name	Lhrh, Phe(5)-δ-Ala(6)-
CAS No.	114681-51-5
Molecular Formula	C56H78N16O12
Molecular Weight	1119.3 g/mol
Synonyms	δ-Ala(6)-LHRH; [D-Ala6]-LHRH; Luteinizing Hormone-Releasing Hormone (5-Phe, 6-D-Ala) analog; Gonadorelin (5-Phe, 6-D-Ala) analog; LH-RH (5-Phe, 6-D-Ala); pGlu-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2; LHRH agonist analog; GnRH analog (D-Ala6)
EINECS	Contact for details

Quality Control

Our Lhrh, Phe(5)-δ-Ala(6)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Within ± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.