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3-o-(2-Acetamido-6-o-(n-Acetylneuraminyl)-2-Deoxygalactosyl)Serine CAS NO 114661-01-7
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CAS No.:114661-01-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-o-(2-Acetamido-6-o-(n-Acetylneuraminyl)-2-Deoxygalactosyl)Serine is a complex, high-purity glycosylated amino acid derivative, specifically a sialylated glycopeptide building block. This compound is of significant value in advanced biochemical research and pharmaceutical development due to its role in studying and mimicking complex biological structures. It is primarily needed by research institutions and biopharmaceutical companies focused on glycobiology, neuraminidase inhibitors, and the synthesis of glycoconjugate vaccines. Our supply ensures consistent quality and reliable availability for critical R&D and production workflows.
Application
- Glycobiology Research: Used as a key intermediate or reference standard in the study of sialic acid-containing glycoproteins and glycolipids.
- Pharmaceutical Development: Serves as a crucial building block for the synthesis of novel glycopeptide-based therapeutics and vaccine candidates.
- Enzyme Substrate Studies: Acts as a specific substrate for neuraminidase (sialidase) enzymes to study enzyme kinetics and inhibition.
- Bioconjugation: Utilized in the development of targeted drug delivery systems and diagnostic probes through site-specific conjugation.
- Standards and Calibration: Provides a high-purity analytical standard for mass spectrometry and chromatography in proteomics and glycomics.
- Cell Signaling Research: Applied in investigations of cell-cell recognition, immune response modulation, and pathogen-host interactions mediated by sialylated structures.
Basic Information
| Product Name | 3-o-(2-Acetamido-6-o-(n-Acetylneuraminyl)-2-Deoxygalactosyl)Serine |
| CAS No. | 114661-01-7 |
| Molecular Formula | C25H41N3O16 |
| Molecular Weight | 639.61 g/mol |
| Synonyms | Serine, 3-O-[2-(acetylamino)-2-deoxy-6-O-(N-acetyl-α-neuraminosyl)-D-galactopyranosyl]-; α-Neu5Ac-(2→6)-β-D-GalNAc-Ser; Sialyl-Tn antigen Serine conjugate; N-Acetylneuraminyl-(α2→6)-N-acetylgalactosamine-Ser; O-(N-Acetyl-α-neuraminosyl)-(2→6)-O-(2-acetamido-2-deoxy-β-D-galactopyranosyl)-L-serine; Glycopeptide building block (sialylated); 114661-01-7 |
| EINECS | Contact for details |
Quality Control
Our 3-o-(2-Acetamido-6-o-(n-Acetylneuraminyl)-2-Deoxygalactosyl)Serine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 5.0% |
| Heavy Metals | ≤ 20 ppm |
| Residual Solvents (GC) | Meets ICH guidelines |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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