Description

n-Acetyl-9-o-(n-Acetyl-β-Neuraminosyl)-Neuraminic Acid is a complex sialic acid derivative, specifically a disialic acid, that serves as a critical biochemical intermediate and reference standard. This compound is essential for research and development in glycobiology and the synthesis of more complex oligosaccharides. It is primarily required by pharmaceutical R&D teams, diagnostic developers, and academic researchers focused on carbohydrate chemistry, neuraminidase studies, and the development of glycan-based therapeutics.

Application

• Biochemical Research: Used as a high-purity reference standard and substrate in enzymatic studies, particularly for neuraminidases and sialyltransferases.
• Pharmaceutical Development: Serves as a key intermediate in the synthesis of novel glycoconjugate vaccines and therapeutic oligosaccharides.
• Diagnostic Reagent Production: Employed in the development and calibration of diagnostic assays that detect sialic acid-related enzymes or metabolic pathways.
• Glycobiology Studies: Critical for investigating cell surface recognition, signaling processes, and the role of sialic acids in infection and immunity.
• Standards Manufacturing: Supplied to laboratories and manufacturers for use as an analytical standard to ensure quality control in related products.

Basic Information

Product Name	n-Acetyl-9-o-(n-Acetyl-β-Neuraminosyl)-Neuraminic Acid
CAS No.	114608-45-6
Molecular Formula	C₂₃H₃₈N₂O₁₇
Molecular Weight	614.56 g/mol
Synonyms	Disialic Acid (α2→8); Neu5Acα2-8Neu5Ac; 9-O-Acetyl-N-acetylneuraminic acid-(α2-8)-N-acetylneuraminic acid; Colominic Acid Disaccharide Unit; Di-N-acetylneuraminic acid; 5-Acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosonic acid-(2→8)-5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosonic acid; α2,8-Linked Disialic Acid
EINECS	Contact for details

Quality Control

Our n-Acetyl-9-o-(n-Acetyl-β-Neuraminosyl)-Neuraminic Acid is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.