Description

Ethyl 4-(2-Methoxyphenyl)-6-Methyl-2-Thioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in creating new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of dihydropyrimidinone (DHPM) derivatives, a scaffold with broad biological activity.
• Medicinal Chemistry Research: Used as a core building block for structure-activity relationship (SAR) studies targeting various enzyme inhibitors.
• Library Synthesis: Valuable for generating diverse compound libraries in high-throughput screening for drug discovery programs.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and protein functions.
• Agrochemical Research: Potential intermediate for developing new active ingredients with herbicidal or pesticidal properties.
• Academic Research: Used in universities and institutes for methodological studies in heterocyclic chemistry and asymmetric synthesis.

Basic Information

Product Name	Ethyl 4-(2-Methoxyphenyl)-6-Methyl-2-Thioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
CAS No.	114483-62-4
Molecular Formula	C15H18N2O3S
Molecular Weight	306.38 g/mol
Synonyms	Ethyl 4-(2-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 5-Carbethoxy-4-(2-methoxyphenyl)-6-methyl-3,4-dihydro-2(1H)-pyrimidinethione; 4-(2-Methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester; DHPM Derivative; Biginelli Reaction Product; Dihydropyrimidinone derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Ethyl 4-(2-Methoxyphenyl)-6-Methyl-2-Thioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.