Description

Propionyl-Neuropeptide Y is a chemically modified analog of the endogenous neuropeptide Y (NPY), a potent neuromodulator involved in numerous physiological processes. This propionylated derivative is primarily utilized in advanced biochemical and pharmacological research to study NPY receptor interactions and signaling pathways with enhanced stability. It serves as a critical tool for researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors, particularly for investigating central nervous system disorders, metabolic regulation, and cardiovascular function.

Application

• Neuroscience Research: A key reagent for studying the role of Neuropeptide Y (NPY) in appetite regulation, anxiety, stress response, and memory.
• Drug Discovery & Development: Used as a reference standard or active pharmaceutical ingredient (API) intermediate in the development of novel therapeutics targeting NPY receptors (Y1, Y2, Y4, Y5).
• Biochemical Assays: Employed in receptor binding studies, functional cellular assays, and signal transduction research to elucidate mechanism of action.
• Metabolic Disorder Studies: Applied in research models for obesity, diabetes, and energy homeostasis due to NPY's role in feeding behavior and metabolism.
• Cardiovascular Research: Investigated for its effects on blood pressure, vasoconstriction, and heart function.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in neurobiology and endocrinology.

Basic Information

Product Name	Propionyl-Neuropeptide Y
CAS No.	114453-28-0
Molecular Formula	C192H290N56O57
Molecular Weight	4252.7 g/mol (approximately)
Synonyms	Propionyl-NPY; N-Propionyl-Neuropeptide Y; Propionylated Neuropeptide Y; NPY (Propionyl); [Propionyl]-Neuropeptide Y; Neuropeptide Y Propionate; pNPY
EINECS	Contact for details

Quality Control

Our Propionyl-Neuropeptide Y is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and peptide content analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.