Description

Atrial Natriuretic Factor (7-23), Pro(10)- CAS NO 114284-25-2 is a synthetic peptide fragment derived from the human atrial natriuretic peptide (ANP) hormone. This high-purity biochemical is critical for cardiovascular and renal research, serving as a key reference standard and active pharmaceutical ingredient (API) intermediate. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutics for hypertension, heart failure, and renal disorders.

Application

• Pharmaceutical Reference Standard: Used for the calibration and validation of analytical methods (HPLC, MS) in drug development and quality control laboratories.
• Biochemical Research Reagent: Essential for in vitro and in vivo studies investigating the natriuretic peptide system, receptor binding assays, and signal transduction pathways.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key building block in the synthesis of longer ANP analogs or novel peptide-based therapeutics.
• Diagnostic Kit Development: Employed in the production of immunoassays and diagnostic kits for measuring natriuretic peptide levels in clinical samples.
• Cardiovascular Disease Research: A vital tool for studying mechanisms of blood pressure regulation, fluid balance, and cardiac hypertrophy.

Basic Information

Product Name	Atrial Natriuretic Factor (7-23), Pro(10)- CAS NO 114284-25-2
CAS No.	114284-25-2
Molecular Formula	C79H124N24O23S2
Molecular Weight	1841.1 g/mol
Synonyms	ANF (7-23), Pro(10)-; Atriopeptin (7-23), Pro(10)-; ANP (7-23), Pro(10)-; Atrial Natriuretic Peptide Fragment 7-23, Proline-10; H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Pro-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-OH (Disulfide bridge: Cys7-Cys23); Cardionatrin (7-23), Pro(10)-; Auriculin (7-23), Pro(10)-
EINECS	Contact for details

Quality Control

Our Atrial Natriuretic Factor (7-23), Pro(10)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.