Description

Atrial Natriuretic Factor (7-23)Amide is a synthetic peptide fragment of the endogenous cardiac hormone, Atrial Natriuretic Peptide (ANP). This compound is a critical research tool for investigating cardiovascular physiology, renal function, and natriuretic peptide receptor signaling pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on cardiovascular drug discovery and metabolic studies.

Application

• Cardiovascular Research: Used as a reference standard and active agent in studies of blood pressure regulation, vasodilation, and heart failure models.
• Renal Physiology Studies: Employed to investigate natriuresis, diuresis, and the modulation of renal sodium and water excretion.
• Receptor Binding Assays: Serves as a key ligand in competitive binding studies to characterize and quantify ANP receptor subtypes (NPR-A, NPR-C).
• Biochemical Pathway Analysis: A tool for elucidating the cGMP-mediated signaling cascades activated by natriuretic peptides.
• Pharmaceutical Development: Used in the screening and validation of novel therapeutic candidates targeting the natriuretic peptide system.
• In Vitro Diagnostics (IVD) Development: May be employed as a calibrator or component in the development of immunoassays for ANP-related biomarkers.

Basic Information

Product Name	Atrial Natriuretic Factor (7-23)Amide
CAS No.	114191-94-5
Molecular Formula	C78H122N24O21S2
Molecular Weight	1771.1 g/mol
Synonyms	ANF (7-23) amide; Atriopeptin (7-23) amide; ANP (7-23) amide; Atrial Natriuretic Peptide (7-23) amide; Cardionatrin (7-23) amide; Auriculin A (7-23) amide; H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-NH2 (Disulfide bridge: Cys7-Cys23)
EINECS	Contact for details

Quality Control

Every batch of Atrial Natriuretic Factor (7-23)Amide is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the exacting standards required for research-grade peptides. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), molecular weight confirmation (by MS), and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider desiccant.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by Mass Spectrometry
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.