Description

H-Ile-Ile-Ile-Oh CAS NO 114148-95-7 is a high-purity tripeptide composed of three consecutive L-isoleucine amino acid residues. This specialized peptide building block is critical for pharmaceutical research and development, particularly in the synthesis of complex peptide-based therapeutics and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in peptide synthesis, medicinal chemistry, and biochemical studies.

Application

• Pharmaceutical Intermediate: A key building block for the solid-phase and solution-phase synthesis of longer therapeutic peptides targeting metabolic disorders, cardiovascular diseases, and other conditions.
• Biochemical Research: Used as a standard or substrate in enzymatic studies, protein-protein interaction research, and structure-activity relationship (SAR) investigations.
• Peptide Library Construction: Essential for creating combinatorial peptide libraries for high-throughput screening in drug discovery programs.
• Cosmeceutical Development: Incorporated into the research of bioactive peptides for advanced skincare formulations aimed at anti-aging or skin barrier repair.
• Academic Research: Serves as a model compound in university and institutional labs for studying peptide synthesis techniques, purification, and characterization.

Basic Information

Product Name	H-Ile-Ile-Ile-Oh
CAS No.	114148-95-7
Molecular Formula	C18H33N3O4
Molecular Weight	355.48 g/mol
Synonyms	Isoleucine-Isoleucine-Isoleucine; L-Ile-L-Ile-L-Ile; Ile-Ile-Ile; Triisoleucine; H-Ile-Ile-Ile-OH; L-Isoleucyl-L-isoleucyl-L-isoleucine; Isoleucyl-isoleucyl-isoleucine; 2-[(2-[(2-Amino-3-methylpentanoyl)amino]-3-methylpentanoyl)amino]-3-methylpentanoic acid
EINECS	Contact for details

Quality Control

Our H-Ile-Ile-Ile-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric purity, and identity confirmation via mass spectrometry (MS) and infrared spectroscopy (IR). Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.