Description

Fmoc-Phe-Odhbt CAS NO 114119-90-3 is a specialized, protected amino acid derivative used as a key building block in solid-phase peptide synthesis (SPPS). This compound matters because it provides a highly reactive ester for efficient coupling reactions, enabling the production of complex peptides with high purity and yield. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of therapeutic peptides, peptide hormones, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an activated ester derivative for the efficient incorporation of phenylalanine (Phe) into growing peptide chains.
• Pharmaceutical Research: A critical intermediate in the synthesis of peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation: Used to create peptide-protein or peptide-small molecule conjugates for targeted drug delivery and diagnostic applications.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for high-throughput screening and drug discovery.
• Academic Research: For studying peptide structure, function, and interactions in biochemistry and molecular biology laboratories.
• Custom Peptide Service Providers: A key raw material for companies offering bespoke peptide synthesis services.

Basic Information

Product Name	Fmoc-Phe-Odhbt
CAS No.	114119-90-3
Molecular Formula	C31H24N2O6
Molecular Weight	520.53 g/mol
Synonyms	Fmoc-Phenylalanine-Odhbt Ester; N-(9-Fluorenylmethoxycarbonyl)-L-phenylalanine 3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl ester; 1,2,3-Benzotriazin-4(3H)-one, 3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-1-oxo-3-phenylpropyl] ester; Fmoc-Phe-ODhbt; Fmoc-L-Phe-Odhbt; ODhbt ester of Fmoc-Phenylalanine; Fmoc-Phenylalanine benzotriazolyl ester derivative
EINECS	Contact for details

Quality Control

Our Fmoc-Phe-Odhbt is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity, suitable for sensitive peptide synthesis applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. Allow the sealed container to reach ambient temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	-15.0° to -25.0° (c=1 in DMF)
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.