Description

2-Chloromethyl-4,6-dimethoxypyrimidine is a versatile and high-value pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its primary commercial value lies in its reactive chloromethyl group, which facilitates efficient alkylation and further functionalization to create complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the production of antiviral agents, kinase inhibitors, and other small-molecule active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Used in the development of specialty polymers, ligands, and functional materials.
• Chemical Research & Development: A versatile reagent for constructing pyrimidine-based libraries in medicinal chemistry and drug discovery programs.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs for bespoke chemical manufacturing.

Basic Information

Product Name	2-Chloromethyl-4,6-dimethoxypyrimidine
CAS No.	114108-86-0
Molecular Formula	C7H9ClN2O2
Molecular Weight	188.61 g/mol
Synonyms	4,6-Dimethoxy-2-(chloromethyl)pyrimidine; 2-(Chloromethyl)-4,6-dimethoxypyrimidine; 4,6-Dimethoxy-2-pyrimidinylmethyl Chloride; 2-Chloromethyl-4,6-dimethoxy-pyrimidine; NSC 405122; Pyrimidine, 2-(chloromethyl)-4,6-dimethoxy-; (4,6-Dimethoxypyrimidin-2-yl)methyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Chloromethyl-4,6-dimethoxypyrimidine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.