Description

Vasotocin, (β-Mercapto-Beta,β-Cyclopentamethylenepropionic Acid)-o-Methyl-Tyr(2)-Thr(4)-Orn(8)-Tyr(9)-Nh2 is a synthetic, non-mammalian neurohypophysial hormone analog with a modified cyclic structure. This compound is of significant interest in biochemical and pharmacological research due to its role as a potent vasopressor and antidiuretic agent in non-mammalian vertebrates. It is primarily utilized by research institutions and pharmaceutical development companies focused on neuroendocrinology, comparative physiology, and the development of novel peptide-based therapeutics. The specific structural modifications enhance its stability and receptor binding profile for targeted studies.

Application

• Neuroendocrine Research: Fundamental studies on the vasopressin/oxytocin receptor family and their evolutionary biology.
• Comparative Physiology: Investigation of osmoregulation, cardiovascular function, and social behaviors in avian, reptilian, and amphibian models.
• Peptide Drug Discovery: Serving as a lead compound or a biochemical tool for designing new agonists or antagonists with modified selectivity and pharmacokinetics.
• Receptor Binding Assays: Used in competitive binding studies to characterize and map receptor subtypes and their signaling pathways.
• Biochemical Standard: Acting as a high-purity reference standard in analytical methods such as HPLC and mass spectrometry for quality control in related research.

Basic Information

Product Name	Vasotocin, (β-Mercapto-Beta,β-Cyclopentamethylenepropionic Acid)-o-Methyl-Tyr(2)-Thr(4)-Orn(8)-Tyr(9)-Nh2
CAS No.	114056-26-7
Molecular Formula	C46H68N12O12S
Molecular Weight	1013.2 g/mol
Synonyms	[Arg8]-Vasotocin; Arg-Vasotocin; AVT; (1-(3-Mercaptopropanoic acid)-2-(O-methyl-L-tyrosine)-4-L-threonine-8-L-ornithine-9-L-tyrosinamide)-vasotocin; Cyclo(1-6)-Cys(1)-Tyr(2)-Ile(3)-Gln(4)-Asn(5)-Cys(6)-Pro(7)-Arg(8)-Gly(9)-NH2 (cyclic analog); 8-Arginine Vasotocin; Vasotocin amide; Non-mammalian antidiuretic hormone
EINECS	Contact for details

Quality Control

Our Vasotocin analog is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. We adhere to high-purity research-grade standards suitable for in-vitro and in-vivo applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccant and under an inert atmosphere to maintain stability. Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content (Amino Acid Analysis)	≥ 80.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.