Description

2,4,6-Trinitrophenyl-Tyrosyl-Valyl-Glycine is a specialized synthetic peptide derivative, primarily utilized as a key intermediate in advanced biochemical research and pharmaceutical development. Its core value lies in providing a high-purity, structurally defined building block for the synthesis of more complex peptides and for use in proteomics studies. This compound is essential for researchers and manufacturers in the fields of medicinal chemistry, peptide-based drug discovery, and biochemical assay development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a substrate or reference standard in enzymatic studies and proteomics research to understand protein interactions and functions.
• Protease Substrate Development: Acts as a model compound for designing and testing specific protease inhibitors and activity assays.
• Antibody Production: Can be conjugated to carrier proteins for the generation of specific antibodies against tyrosine-containing peptide sequences.
• Chemical Biology Tool: Employed in the study of signal transduction pathways and post-translational modifications due to its tyrosine moiety.
• Quality Control Standard: Used as an analytical reference standard in HPLC and mass spectrometry for peptide purity and identity confirmation.

Basic Information

Product Name	2,4,6-Trinitrophenyl-Tyrosyl-Valyl-Glycine
CAS No.	114043-34-4
Molecular Formula	C25H28N6O11
Molecular Weight	588.52 g/mol
Synonyms	TNP-Tyr-Val-Gly; 2,4,6-Trinitrophenyl-L-tyrosyl-L-valylglycine; TNP-YVG-OH; Glycine, N-[N-[N-[2,4,6-trinitrophenyl)-L-tyrosyl]-L-valyl]-; L-Tyrosine, N-[2,4,6-trinitrophenyl]-, L-valylglycine deriv.; Trinitrophenylated Tyr-Val-Gly tripeptide
EINECS	Contact for details

Quality Control

Our 2,4,6-Trinitrophenyl-Tyrosyl-Valyl-Glycine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee consistent quality and traceability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.