Description

n-Fluoro-n-Propyl-p-Toluenesulfonamide is a specialized fluorinated sulfonamide derivative, serving as a valuable synthetic intermediate and building block in advanced organic chemistry. Its core value lies in the introduction of a fluorine atom and a sulfonamide-protected amine group, enabling precise molecular modifications for performance enhancement. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science sectors for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Fluorination Reagent Precursor: Serves as a precursor or reagent in nucleophilic fluorination reactions to introduce fluorine into complex organic scaffolds.
• Material Science: Employed in the synthesis of fluorinated polymers, liquid crystals, and specialty surfactants for enhanced thermal and chemical resistance.
• Chemical Biology Probe Development: Utilized as a tagged molecule or linker in the creation of probes for studying enzyme mechanisms and protein interactions.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct complex biaryl and amine-containing structures.

Basic Information

Product Name	n-Fluoro-n-Propyl-p-Toluenesulfonamide
CAS No.	113845-16-2
Molecular Formula	C10H14FNO2S
Molecular Weight	231.29 g/mol
Synonyms	1-Fluoropropane-1-sulfonamide, N-(p-Tolyl); N-Fluoro-N-propyl-4-methylbenzenesulfonamide; p-Toluenesulfonyl fluoride propylamide; N-Propyl-N-fluoro-p-toluenesulfonamide; 4-Methyl-N-(1-fluoropropyl)benzenesulfonamide; 1-Fluoro-N-(4-methylphenylsulfonyl)propan-1-amine; Tosyl fluoride propylamide; F-propyl tosylamide
EINECS	Contact for details

Quality Control

Our n-Fluoro-n-Propyl-p-Toluenesulfonamide is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.