Description

N1,N12-Diethylspermine Tetrahydrochloride is a chemically modified polyamine derivative, specifically a tetra-hydrochloride salt of diethylspermine. This compound is of significant interest in biochemical and pharmacological research due to its role as a potent modulator of polyamine metabolism and cellular processes. It serves as a critical intermediate and research tool for scientists in pharmaceutical development, oncology research, and molecular biology. The product is supplied as a high-purity material to ensure reliable and reproducible experimental results.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to polyamine biosynthesis and catabolism.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel therapeutic agents targeting cell proliferation.
• Oncology Studies: Investigated for its effects on cancer cell growth, apoptosis, and as a potential chemosensitizer.
• Neuropharmacology: Explored in research concerning neuroprotection, neurodegenerative diseases, and synaptic function.
• Molecular Biology: Utilized in studies of DNA conformation, gene expression, and protein-nucleic acid interactions.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	N1,N12-Diethylspermine Tetrahydrochloride
CAS No.	113812-15-0
Molecular Formula	C12H34Cl4N4
Molecular Weight	380.23 g/mol
Synonyms	N1,N12-Diethylspermine 4HCl; Diethylspermine tetrahydrochloride; 1,12-Diethyl-4,9-diazadodecane-1,12-diamine tetrahydrochloride; N,N'-Diethylspermine tetrahydrochloride; DESpm•4HCl; N1,N12-Bis(ethyl)spermine tetrahydrochloride; Polyamine analogue DESpm tetrahydrochloride
EINECS	Contact for details

Quality Control

Our N1,N12-Diethylspermine Tetrahydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods, and residual solvent analysis to ensure it meets rigorous standards for research applications. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.