Description

2,3,6-Trifluorophenol CAS NO 113798-74-6 is a high-purity fluorinated phenol derivative, a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Building block for advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated components for electronic displays and organic light-emitting diodes due to its influence on molecular polarity and alignment.
• Polymer Modification: Serves as a monomer or modifier to introduce fluorine into polymer backbones, improving chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the trifluorophenol moiety into complex molecular architectures.
• Material Science Research: Utilized in developing novel fluorinated compounds for coatings, adhesives, and specialty solvents.

Basic Information

Product Name	2,3,6-Trifluorophenol
CAS No.	113798-74-6
Molecular Formula	C6H3F3O
Molecular Weight	148.08 g/mol
Synonyms	2,3,6-Trifluorophenol; Phenol, 2,3,6-trifluoro-; 2,3,6-Trifluoro-1-hydroxybenzene; 1-Hydroxy-2,3,6-trifluorobenzene; 2,3,6-Trifluorobenzenol; NSC 405124; AI3-52284
EINECS	Contact for details

Quality Control

Our 2,3,6-Trifluorophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and lot-to-lot consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our production adheres to cGMP standards where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or suitably opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	45 - 50 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.