Description

Z-Phe-Arg-Ome Hcl CAS NO 113715-88-1 is a high-purity, protected tripeptide derivative, specifically a benzyloxycarbonyl (Z)-protected phenylalanyl-arginine methyl ester hydrochloride salt. This compound serves as a critical building block and key intermediate in advanced organic synthesis, particularly in the production of complex peptides and protease inhibitors. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science research sectors who require reliable, high-quality intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: Key building block in the solid-phase and solution-phase synthesis of therapeutic peptides and peptidomimetics.
• Protease Inhibitor Research: Used as a substrate analog or intermediate in the development and study of serine protease inhibitors, including those targeting thrombin and trypsin-like enzymes.
• Biochemical Tool: Employed in enzymatic assays and kinetic studies to investigate protease activity and mechanism.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of drug candidates.
• Academic & Industrial R&D: A valuable reagent for chemical biology research and the discovery of new bioactive compounds.

Basic Information

Product Name	Z-Phe-Arg-Ome Hcl
CAS No.	113715-88-1
Molecular Formula	C27H37N6O5 • HCl
Molecular Weight	577.09 g/mol
Synonyms	Benzyloxycarbonyl-L-phenylalanyl-L-arginine methyl ester hydrochloride; Z-Phe-Arg-OMe • HCl; Nα-Carbobenzoxy-L-phenylalanyl-L-arginine methyl ester hydrochloride; CBZ-Phe-Arg-OMe hydrochloride; N-CBZ-L-phenylalanyl-L-arginine methyl ester hydrochloride; L-Phenylalanyl-N2-[(phenylmethoxy)carbonyl]-N5-(diaminomethylidene)-L-ornithine methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Z-Phe-Arg-Ome Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral purity verification, and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.