Description

Bradykinin, (Hydroxy-Pro)(3)-Lys- is a synthetic, modified peptide analog of the endogenous vasoactive peptide bradykinin. This compound is of significant value for advanced biochemical and pharmacological research due to its specific structural modifications, which can alter receptor binding affinity and metabolic stability. It is primarily needed by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in cardiovascular research, inflammation studies, and the development of novel peptide-based therapeutics.

Application

• Biochemical Research: Used as a reference standard or tool compound in studies investigating the kallikrein-kinin system, receptor-ligand interactions, and signal transduction pathways.
• Pharmacological Studies: Employed in in vitro and in vivo models to study vasodilation, blood pressure regulation, pain mediation, and inflammatory responses.
• Drug Discovery & Development: Serves as a key intermediate or analog in the design and synthesis of new peptide drugs targeting bradykinin receptors (B1 and B2).
• Diagnostic Development: Potential use in the development of immunoassays or diagnostic kits for measuring kinin levels or related enzymatic activity.
• Academic Research: Utilized in university and institutional labs for fundamental research in physiology, neurobiology, and peptide chemistry.

Basic Information

Product Name	Bradykinin, (Hydroxy-Pro)(3)-Lys-
CAS No.	113662-39-8
Molecular Formula	C50H78N14O13
Molecular Weight	1059.25 g/mol
Synonyms	Bradykinin, [Hyp3, Lys]-; [Hyp3, Lys]-Bradykinin; (Hydroxyproline3, Lysine)-Bradykinin; Lys0-Hyp3-Bradykinin; Arg-Pro-Pro-Gly-Phe-Ser-Pro-Hyp-Arg-Lys; H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Hyp-Arg-Lys-OH; Modified Bradykinin Peptide
EINECS	Contact for details

Quality Control

Our Bradykinin, (Hydroxy-Pro)(3)-Lys- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are available upon request to ensure compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.