Description

3'-Amino-4'-Fluoroacetanilide is a high-purity fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a protected amine and a halogen handle for selective functionalization, enabling the efficient construction of complex molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing fluorinated aromatic systems.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and stability.
• Dye and Pigment Manufacturing: Used in the production of specialized dyes and pigments, where the amino and fluoro groups influence color properties and fastness.
• Material Science Research: Intermediate for creating advanced polymers, liquid crystals, or organic electronic materials requiring specific aromatic amine functionalities.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating carbon-nitrogen bonds.
• Chemical Research & Development: Versatile starting material in academic and industrial R&D for exploring new synthetic pathways and novel compound libraries.

Basic Information

Product Name	3'-Amino-4'-Fluoroacetanilide
CAS No.	113596-04-6
Molecular Formula	C8H9FN2O
Molecular Weight	168.17 g/mol
Synonyms	N-(3-Amino-4-fluorophenyl)acetamide; 1-(3-Amino-4-fluorophenyl)ethanone; 4'-Fluoro-3'-aminoacetanilide; 3-Amino-4-fluoroacetanilide; 4-Fluoro-3-aminoacetanilide; Acetamide, N-(3-amino-4-fluorophenyl)-; 3-Acetamido-4-fluoroaniline
EINECS	Contact for details

Quality Control

Our 3'-Amino-4'-Fluoroacetanilide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.