Description

Dansyl-Tyr-Val-Gly CAS NO 113527-49-4 is a dansyl-labeled tetrapeptide derivative, serving as a critical tool compound in biochemical and pharmacological research. Its core value lies in the dansyl fluorophore, which provides a sensitive handle for fluorescence-based detection, quantification, and mechanistic studies. This product is essential for researchers and developers in pharmaceutical R&D, proteomics, and enzymology who require high-purity, well-characterized peptide probes.

Application

• Fluorescent Substrate for Enzyme Assays: Used as a specific, sensitive substrate to study the kinetics and inhibition of proteases and peptidases.
• Biomolecular Interaction Studies: Employed in fluorescence polarization (FP) or fluorescence resonance energy transfer (FRET) assays to investigate protein-protein or protein-ligand interactions.
• Protease Activity Profiling: Aids in the screening and characterization of novel enzyme targets in drug discovery pipelines.
• Cell-Based Imaging Probes: Can be utilized to develop probes for tracking enzymatic activity within cellular environments.
• Chromatographic Standards: Serves as a high-purity reference standard for method development and validation in analytical HPLC and LC-MS.
• Peptide Chemistry Research: Acts as a model compound for studying fluorescence quenching, energy transfer, and peptide labeling techniques.

Basic Information

Product Name	Dansyl-Tyr-Val-Gly
CAS No.	113527-49-4
Molecular Formula	C32H39N5O7S
Molecular Weight	637.75 g/mol
Synonyms	Dansyl-Tyr-Val-Gly-OH; N-Dansyl-L-tyrosyl-L-valylglycine; 5-(Dimethylamino)naphthalene-1-sulfonyl-L-tyrosyl-L-valylglycine; DNS-Tyr-Val-Gly; Dns-YVG-OH; L-Tyrosine, N-[N-[N-[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-L-tyrosyl]-L-valyl]glycine
EINECS	Contact for details

Quality Control

Our Dansyl-Tyr-Val-Gly is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant standards for research-grade biochemicals, and custom synthesis and purification to specific specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.