Description

Phenol, 3-Amino-2,4,6-Trifluoro- is a fluorinated aniline derivative, serving as a versatile and high-value building block in advanced organic synthesis. Its unique structure, featuring both amino and phenol groups on a trifluoromethylated benzene ring, makes it critical for introducing fluorine atoms and specific functional handles into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced properties. CAS No. 113512-72-4.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the fluorine atoms improve metabolic stability and bioavailability.
• Material Science: Serves as a monomer or precursor for specialty polymers, liquid crystals, and advanced organic electronic materials.
• Dye and Pigment Industry: Intermediate for producing high-performance, light-fast fluorinated dyes and pigments.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new fluorination reactions and creating complex molecular architectures.
• Ligand Synthesis: Precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Phenol, 3-Amino-2,4,6-Trifluoro-
CAS No.	113512-72-4
Molecular Formula	C6H4F3NO
Molecular Weight	163.10 g/mol
Synonyms	2,4,6-Trifluoro-3-aminophenol; 3-Amino-2,4,6-trifluorophenol; 3-Amino-2,4,6-trifluoro-1-hydroxybenzene; 2,4,6-Trifluoro-3-hydroxyaniline; 3-Hydroxy-2,4,6-trifluoroaniline; TAFP; 113512-72-4 (CAS Registry)
EINECS	Contact for details

Quality Control

Our Phenol, 3-Amino-2,4,6-Trifluoro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay (by HPLC), impurity profile, and physical characterization. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.