Description

5-Amino-2,4-Difluorophenol is a versatile fluorinated aromatic amine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both amino and phenolic functional groups on a difluorinated benzene ring, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of active ingredients, as well as by manufacturers of specialty dyes and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a fluorinated phenolic scaffold.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the difluorophenol moiety enhances biological activity and stability.
• Dye and Pigment Manufacturing: Serves as a building block for producing specialized fluorinated dyes and pigments with unique color fastness and spectral properties.
• Liquid Crystal and OLED Materials: Employed in the research and production of fluorinated components for electronic display materials.
• Polymer Modification: Acts as a monomer or additive to introduce fluorine atoms into polymer chains, improving chemical resistance and surface properties.
• Cross-coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) for constructing complex aromatic systems.

Basic Information

Item	Detail
Product Name	5-Amino-2,4-Difluorophenol
CAS No.	113512-71-3
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	2,4-Difluoro-5-aminophenol; 5-Amino-2,4-difluorophenol; 3-Amino-4,6-difluorophenol; 2,4-Difluoro-5-hydroxyaniline; 5-Amino-2,4-DFP; AI3-52062; ZINC000103014509; CCRIS 9387
EINECS	Contact for details

Quality Control

Our 5-Amino-2,4-Difluorophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	145 - 150 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.