Description

Tyrosyl-Prolyl-Leucyl-Glycine is a synthetic tetrapeptide with the sequence Tyr-Pro-Leu-Gly. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a peptide fragment and potential biological activity. It serves as a critical building block and reference standard for researchers in neurobiology and peptide chemistry. Industries requiring high-purity peptide intermediates for drug discovery, diagnostic assays, or biochemical studies are the primary users of this material.

Application

• Pharmaceutical Research & Development: Used as a key intermediate or reference standard in the synthesis and study of larger, biologically active peptides and potential drug candidates.
• Neurobiological Studies: Employed in research investigating peptide interactions with neurological receptors and pathways, given its sequence relevance.
• Biochemical Reagent: Functions as a substrate or inhibitor in enzymatic assays to study protease activity and specificity.
• Cosmeceutical Development: Investigated for potential applications in advanced skincare formulations targeting specific cellular signaling.
• Academic & Institutional Research: Serves as a pure standard for mass spectrometry calibration, chromatography method development, and peptide structure-activity relationship (SAR) studies.
• Diagnostic Kit Manufacturing: Utilized in the production of calibration standards or components for immunoassays and other diagnostic tests.

Basic Information

Product Name	Tyrosyl-Prolyl-Leucyl-Glycine
CAS No.	113480-19-6
Molecular Formula	C24H35N5O6
Molecular Weight	489.57 g/mol
Synonyms	Tyr-Pro-Leu-Gly; YPLG; TPLG; H-Tyr-Pro-Leu-Gly-OH; L-Tyrosyl-L-prolyl-L-leucyl-glycine; Tyrosine-proline-leucine-glycine; Tetrapeptide YPLG; 113480-19-6
EINECS	Contact for details

Quality Control

Every batch of Tyrosyl-Prolyl-Leucyl-Glycine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with exacting standards for research and development. A comprehensive Certificate of Analysis (COA), detailing purity, assay, and impurity profiles, is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (HPLC)	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.