Description

3-Fluoromethyl Ofloxacin is a synthetic fluoroquinolone derivative, specifically a fluorinated analog of the broad-spectrum antibiotic ofloxacin. This modification is designed to enhance its antibacterial potency and alter its pharmacokinetic profile, making it a valuable intermediate in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and manufacturers in the pharmaceutical industry for the synthesis of next-generation antimicrobial agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel fluoroquinolone-based antibiotics.
• Antimicrobial Research: Used in structure-activity relationship (SAR) studies to develop compounds with improved efficacy against resistant bacterial strains.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the development and scale-up of new antibacterial APIs.
• Biochemical Research: Employed as a tool compound in microbiological and pharmacological studies to investigate bacterial DNA gyrase and topoisomerase IV inhibition.

Basic Information

Item	Detail
Product Name	3-Fluoromethyl Ofloxacin
CAS No.	113472-55-2
Molecular Formula	C19H20FN3O4
Molecular Weight	373.38 g/mol
Synonyms	3-(Fluoromethyl)ofloxacin; (±)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 3-fluoromethyl derivative; Ofloxacin 3-fluoromethyl analog; Fluoromethylofloxacin; 3-FMO
EINECS	Contact for details

Quality Control

Our 3-Fluoromethyl Ofloxacin is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets stringent research-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.