Description

4-Fluoro-3-(trifluoromethoxy)aniline, 97% is a high-purity fluorinated aromatic amine building block of significant commercial importance. This compound is valued for its unique combination of fluorine and trifluoromethoxy substituents, which impart enhanced lipophilicity, metabolic stability, and electronic properties to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) drugs, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine motifs improve biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Dye & Pigment Manufacturing: Acts as an intermediate for creating fluorinated dyes and pigments with unique color fastness and spectral properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Buchwald-Hartwig amination) and as a precursor for heterocyclic compounds in medicinal chemistry.

Basic Information

Product Name	4-Fluoro-3-(trifluoromethoxy)aniline, 97%
CAS No.	113421-98-0
Molecular Formula	C7H5F4NO
Molecular Weight	195.12 g/mol
Synonyms	3-(Trifluoromethoxy)-4-fluoroaniline; 4-Fluoro-3-(trifluoromethoxy)benzenamine; 4-Fluoro-alpha,alpha,α-trifluoro-m-anisidine; 1-Amino-4-fluoro-3-(trifluoromethoxy)benzene; 4-Fluoro-3-trifluoromethoxyaniline; Benzenamine, 4-fluoro-3-(trifluoromethoxy)-; 4-Fluoro-3-trifluoromethoxy phenylamine
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(trifluoromethoxy)aniline, 97% is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its amine functionality and light-sensitive nature, prolonged exposure to air or light should be avoided.

Specification

Item	Specification
Appearance	Light yellow to brown liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.