Description

4-Chloro-2-(4-Fluoro-Phenyl)-Quinazoline is a high-purity, synthetically valuable heterocyclic building block. This compound is critical for research and development in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active quinazoline derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated quinazoline core.
• Material Science: Acts as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO (Contract Research Organization) settings.
• Custom Synthesis: A starting material for the tailored synthesis of more complex, functionalized quinazoline compounds for specific client projects.

Basic Information

Product Name	4-Chloro-2-(4-Fluoro-Phenyl)-Quinazoline
CAS No.	113242-33-4
Molecular Formula	C14H8ClFN2
Molecular Weight	258.68 g/mol
Synonyms	2-(4-Fluorophenyl)-4-chloroquinazoline; 4-Chloro-2-(4-fluorophenyl)quinazoline; Quinazoline, 4-chloro-2-(4-fluorophenyl)-; 4-Chloro-2-(p-fluorophenyl)quinazoline; 113242-33-4; 2-(4-Fluorophenyl)-4-chloro-quinazoline; 4-Chloro-2-(4'-fluorophenyl)quinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(4-Fluoro-Phenyl)-Quinazoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.