Description

8-Ethylguanine is a modified purine nucleobase derivative, serving as a critical building block and reference standard in advanced biochemical research and pharmaceutical development. Its value lies in its role as a key intermediate for synthesizing nucleoside analogs and studying DNA alkylation damage and repair mechanisms. This compound is essential for researchers and manufacturers in the fields of oncology drug discovery, molecular biology, and diagnostic reagent production, where precise chemical tools are required.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a standard and reagent in studies of DNA adduct formation, mutagenesis, and repair pathways.
• Diagnostic Development: Employed in the synthesis of probes and markers for genetic testing and molecular diagnostics.
• Academic & Contract Research: Fundamental material for universities and CROs investigating nucleotide chemistry and metabolism.
• Reference Standard: High-purity grade used for analytical method development, validation, and quality control in regulated labs.

Basic Information

Product Name	8-Ethylguanine
CAS No.	113193-97-8
Molecular Formula	C7H9N5O
Molecular Weight	179.18 g/mol
Synonyms	8-Ethylguanine; 8-Ethyl-1H-purin-6-amine; 8-Ethyl-9H-purin-6-amine; 6-Amino-8-ethylpurine; Guanine, 8-ethyl-; 8-Ethyl-guanine; 8-EtG; 8-Ethylguanine (base)
EINECS	Contact for details

Quality Control

Our 8-Ethylguanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, and custom synthesis to meet specific purity or packaging requirements is available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.