Description

4-Amino-3-Bromo-5-Nitrobenzotrifluoride is a high-value, multi-functional aromatic intermediate featuring amino, bromo, nitro, and trifluoromethyl substituents. This unique combination of functional groups makes it a critical building block for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is essential for chemists and manufacturers in the life sciences sector who require precise and reliable intermediates for developing active ingredients, dyes, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Dye and Pigment Manufacturing: Serves as a core structure for producing high-performance, light-fast azo dyes and organic pigments.
• Liquid Crystal & OLED Materials: Employed in the research and production of specialty chemicals for electronic displays and optoelectronic devices.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Chemical Research & Development: A versatile scaffold in academic and industrial R&D for exploring new chemical entities and material science applications.

Basic Information

Product Name	4-Amino-3-Bromo-5-Nitrobenzotrifluoride
CAS No.	113170-71-1
Molecular Formula	C7H4BrF3N2O2
Molecular Weight	285.02 g/mol
Synonyms	3-Bromo-4-amino-5-nitrobenzotrifluoride; 2-Bromo-6-nitro-4-(trifluoromethyl)aniline; 4-Amino-3-bromo-5-nitro-α,α,α-trifluorotoluene; 2-Bromo-4-trifluoromethyl-6-nitroaniline; 1-Amino-2-bromo-4-nitro-5-(trifluoromethyl)benzene; Benzene, 1-amino-2-bromo-4-nitro-5-(trifluoromethyl)-; 4-(Trifluoromethyl)-2-bromo-6-nitroaniline
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Bromo-5-Nitrobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.