Description

Argipressin, Pro(4)-Hydroxy-Pro(7)- is a synthetic analogue of the endogenous neurohypophysial hormone vasopressin, specifically modified to enhance its stability and pharmacological profile. This high-purity peptide is critical for research and development in advanced pharmaceutical applications, offering a reliable reference standard and active pharmaceutical ingredient (API). It is primarily utilized by biotechnology firms, pharmaceutical R&D laboratories, and academic research institutions focused on endocrinology, renal function, and cardiovascular research.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for quality control and analytical method development in drug manufacturing.
• Active Pharmaceutical Ingredient (API): Serves as a key component in the formulation of therapeutic agents targeting conditions like diabetes insipidus or certain bleeding disorders.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate vasopressin receptor (V1a, V1b, V2) signaling pathways and physiological responses.
• Diagnostic Development: Utilized in the development and calibration of immunoassays and diagnostic kits for hormone level detection.
• Neuroscience & Endocrinology Studies: Applied in research exploring the role of vasopressin in memory, social behavior, stress response, and fluid homeostasis.

Basic Information

Product Name	Argipressin, Pro(4)-Hydroxy-Pro(7)-
CAS No.	112953-10-3
Molecular Formula	C46H65N13O12S2
Molecular Weight	1040.2 g/mol
Synonyms	[4-Hydroxyproline7]-Vasopressin; [Hyp7]-Vasopressin; 4-Hydroxy-Pro7-Argipressin; Vasopressin, 7-L-hydroxyproline-; Desmopressin analogue; 1-(3-Mercaptopropanoic acid)-2-(O-ethyl-D-tyrosine)-4-L-threonine-8-L-arginine-9-L-proline-vasopressin, 7-hydroxyproline-; Argipressin, 7-hydroxyproline-
EINECS	Contact for details

Quality Control

Our Argipressin, Pro(4)-Hydroxy-Pro(7)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for related substances and residual solvents, ensuring it meets high-grade standards suitable for research and pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be kept under desiccated conditions upon opening. For long-term storage, keep the primary container sealed in a secondary protective container.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.