Description

Argipressin, Hydroxy-Pro(4)- CAS NO 112935-96-3 is a synthetic analogue of the endogenous neurohypophyseal hormone vasopressin, specifically modified at the fourth position with a hydroxyproline residue. This modification is significant for research into the structure-activity relationships of vasopressin and its receptor interactions. It is a critical compound for biochemical and pharmacological research, particularly in studies related to renal function, cardiovascular regulation, and central nervous system disorders. This high-purity peptide is essential for academic institutions, pharmaceutical R&D laboratories, and biotechnology companies engaged in peptide hormone research and drug discovery.

Application

• Biochemical Research: Used as a reference standard and tool compound for studying vasopressin receptor (V1a, V1b, V2) binding affinity and signal transduction pathways.
• Pharmacological Studies: Investigated for its effects on blood pressure regulation, renal water reabsorption, and platelet aggregation in preclinical models.
• Neuroscience Research: Applied in studies exploring the role of vasopressin analogues in social behavior, memory, and stress response within the central nervous system.
• Drug Discovery & Development: Serves as a key intermediate or parent molecule for the design and synthesis of novel therapeutic peptides targeting vasopressin-related disorders.
• Analytical Standard: Employed as a high-purity calibrant in HPLC, LC-MS, and other analytical methods for quality control and method validation in peptide analysis.

Basic Information

Item	Detail
Product Name	Argipressin, Hydroxy-Pro(4)- CAS NO 112935-96-3
CAS No.	112935-96-3
Molecular Formula	C₄₆H₆₅N₁₃O₁₂S₂
Molecular Weight	1048.2 g/mol
Synonyms	[4-Hydroxyproline]Argipressin; [Hyp⁴]-Argipressin; 4-Hydroxyproline Vasopressin; [Hydroxyproline⁴]-Vasopressin; 8-Arginine Vasopressin, 4-Hydroxyproline analogue; Vasopressin, 4-hydroxyproline-; (4-Hydroxyproline)-Argipressin
EINECS	Contact for details

Quality Control

Our Argipressin, Hydroxy-Pro(4)- CAS NO 112935-96-3 is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC)	≤ 12.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.