Description

Z-Sar-Pro-Arg-OH is a synthetic, high-purity peptide building block and protease inhibitor. This compound is critical for advanced biochemical research and pharmaceutical development, particularly in the study of enzyme kinetics and the design of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in peptide synthesis and drug discovery programs.

Application

• Biochemical Research: Used as a specific substrate or inhibitor in enzymatic assays to study serine proteases like thrombin and trypsin.
• Pharmaceutical R&D: Serves as a key intermediate or a pharmacophore model in the development of novel anticoagulant and anti-inflammatory drug candidates.
• Peptide Synthesis: Acts as a protected peptide fragment for solid-phase or solution-phase synthesis of larger, more complex peptide sequences.
• Proteomics: Employed in activity-based protein profiling (ABPP) to identify and characterize protease activity in complex biological samples.
• Diagnostic Reagent Development: Utilized in the formulation of specialized kits and reagents for clinical diagnostics and research.

Basic Information

Product Name	Z-Sar-Pro-Arg-OH
CAS No.	112898-31-4
Molecular Formula	C24H36N6O7
Molecular Weight	520.58 g/mol
Synonyms	Benzyloxycarbonyl-sarcosyl-prolyl-arginine; Z-Sar-Pro-Arg; Z-Sar-Pro-Arg-OH; Carbobenzoxy-Sar-Pro-Arg-OH; Nα-Carbobenzyloxy-sarcosyl-L-prolyl-L-arginine; Thrombin Inhibitor Z-Sar-Pro-Arg-OH; Boc-Sar-Pro-Arg-OH (common alternate); Sar-Pro-Arg-Z (alternate naming)
EINECS	Contact for details

Quality Control

Our Z-Sar-Pro-Arg-OH is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Assay (Titration)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.