Description

n-Formyl-Met-Leu-Phe-o-Fluorobenzylamide is a synthetic peptide derivative, specifically a formylated tripeptide chemotactic peptide analog. This compound is a valuable biochemical tool used extensively in research to study and modulate the function of formyl peptide receptors (FPRs) on neutrophils and other immune cells. It serves as a potent and selective agonist, enabling the investigation of inflammatory pathways, leukocyte chemotaxis, and immune signaling. This product is essential for researchers and developers in the fields of immunology, pharmacology, and drug discovery.

Application

• Immunological Research: Used as a potent agonist for formyl peptide receptors (FPRs) to study neutrophil activation, chemotaxis, and degranulation in vitro.
• Inflammation Studies: A key tool for modeling and investigating the molecular mechanisms underlying acute and chronic inflammatory responses.
• Signal Transduction Pathways: Employed to dissect intracellular signaling cascades initiated by G-protein coupled receptors (GPCRs) in immune cells.
• Drug Discovery & Screening: Serves as a reference standard and active agent in high-throughput screening assays to identify novel anti-inflammatory compounds or FPR antagonists.
• Cell Biology: Utilized to induce controlled oxidative bursts and study calcium flux in phagocytic cells.
• Biochemical Reagent: Acts as a critical component in buffer systems and assay kits designed for immune cell function analysis.

Basic Information

Product Name	n-Formyl-Met-Leu-Phe-o-Fluorobenzylamide
CAS No.	112898-02-9
Molecular Formula	C33H45FN4O5S
Molecular Weight	628.80 g/mol
Synonyms	fMLF-o-F; N-Formyl-Met-Leu-Phe-o-fluorobenzyl amide; Formyl-Met-Leu-Phe-o-fluorobenzylamide; fMLP-o-F analog; fMLF-o-Fluorobenzylamide; Formyl Peptide Receptor Agonist; Chemotactic Peptide fMLF Derivative; For-Met-Leu-Phe-o-F-BZA
EINECS	Contact for details

Quality Control

Our n-Formyl-Met-Leu-Phe-o-Fluorobenzylamide is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and NMR for structural verification. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to cGMP guidelines where applicable to support our clients in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, keep under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.