Description

2-Chloro-5-Fluoro-4-Thiocyanopyrimidine is a high-value halogenated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring chloro, fluoro, and thiocyano functional groups, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in antiviral and anticancer research programs.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, and insecticides, leveraging its halogenated pyrimidine core.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential building block for creating specialized polymers or ligands with specific electronic properties.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical production.

Basic Information

Product Name	2-Chloro-5-Fluoro-4-Thiocyanopyrimidine
CAS No.	112889-53-9
Molecular Formula	C5HClFN3S
Molecular Weight	189.60 g/mol
Synonyms	4-Thiocyanato-2-chloro-5-fluoropyrimidine; 2-Chloro-5-fluoro-4-pyrimidinethiocyanate; 2-Chloro-5-fluoropyrimidine-4-thiocyanate; 5-Fluoro-2-chloro-4-thiocyanatopyrimidine; 112889-53-9; 2-Chloro-5-fluoro-4-thiocyanato-pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluoro-4-Thiocyanopyrimidine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.