Description

Fmoc-D-Tyr-Oh CAS NO 112883-29-1 is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring precise stereochemical control in the construction of complex peptides and peptidomimetics. It is primarily utilized in pharmaceutical R&D, biotechnology, and academic laboratories for the development of therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key building block for the automated, stepwise assembly of custom peptide sequences.
• Pharmaceutical Research: For the discovery and development of novel peptide-based therapeutics, including hormones, antibiotics, and targeted drug conjugates.
• Bioconjugation: Used to introduce tyrosine residues with an orthogonal Fmoc-protected carboxylic acid group for site-specific labeling or cross-linking.
• Combinatorial Chemistry: Serves as a valuable reagent in libraries for high-throughput screening of bioactive compounds.
• Academic & Biochemical Studies: Employed in studying protein-protein interactions, enzyme substrates, and receptor ligands.
• Production of Chiral Intermediates: Acts as a starting material for the synthesis of more complex, optically active molecules.

Basic Information

Product Name	Fmoc-D-Tyr-Oh
CAS No.	112883-29-1
Molecular Formula	C24H21NO5
Molecular Weight	403.43 g/mol
Synonyms	Fmoc-D-Tyrosine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-tyrosine; (R)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoic acid; Fmoc-D-Tyr-OH; Fmoc-D-Tyrosine-OH; N-Fmoc-D-tyrosine; D-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our Fmoc-D-Tyr-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation (IR, NMR). We provide Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; desiccants are recommended for long-term storage. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.5%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.