Description

5-Bromo-2,4-Difluoro-3-Methylbenzenamine is a high-purity, multi-functional aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of bromine and fluorine substituents, which enable precise molecular modifications for developing novel compounds with targeted properties. This intermediate is essential for R&D and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogenated motifs into their molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the difluoro and bromo groups contribute to biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating fluorinated aromatic components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance thermal stability, chemical resistance, and specific optical properties.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of complex, halogenated dyes and high-performance pigments.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine atom.

Basic Information

Product Name	5-Bromo-2,4-Difluoro-3-Methylbenzenamine
CAS No.	112822-79-4
Molecular Formula	C7H6BrF2N
Molecular Weight	222.03 g/mol
Synonyms	3-Amino-5-bromo-2,4-difluorotoluene; 5-Bromo-2,4-difluoro-3-methylaniline; 2,4-Difluoro-5-bromo-3-methylbenzenamine; 3-Methyl-5-bromo-2,4-difluoroaniline; Benzenamine, 5-bromo-2,4-difluoro-3-methyl-; 5-Bromo-2,4-difluoro-3-methylphenylamine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,4-Difluoro-3-Methylbenzenamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.