Description

Gatifloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic. It is valued for its potent activity against a wide range of Gram-positive and Gram-negative bacteria, including atypical pathogens. This compound is primarily utilized in the pharmaceutical industry for the research and development of antibacterial formulations. Its efficacy makes it a critical component in addressing complex bacterial infections.

Application

• Pharmaceutical Intermediates: Serves as a key active pharmaceutical ingredient (API) in the synthesis of antibacterial drugs.
• Ophthalmic Solutions: Used in the development of eye drop formulations for treating bacterial conjunctivitis and corneal ulcers.
• Veterinary Medicine: Employed in research for creating antibacterial treatments for livestock and companion animals.
• Microbiological Research: Acts as a standard or inhibitor in studies of bacterial resistance mechanisms and antibiotic efficacy.
• Clinical Trial Materials: Supplied as a high-purity reference standard for pharmacokinetic and pharmacodynamic studies.

Basic Information

Product Name	Gatifloxacin
CAS No.	112811-59-3
Molecular Formula	C19H22FN3O4
Molecular Weight	375.40 g/mol
Synonyms	Gatifloxacin; AM-1155; BMS-206584; PD-135432; (±)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid; Tequin (brand name); Zymar (brand name)
EINECS	Contact for details

Quality Control

Our Gatifloxacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with relevant pharmaceutical research standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Microbial Limits	Meets standard requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.