Description

1-Cyclopropyl-6-Fluoro-8-Methoxy-4-Oxo-7-(Piperazin-1-Yl)1,4-Dihydroquinoline-3-Carboxylic Acid CAS NO 112811-57-1 is a high-purity pharmaceutical intermediate and a key structural moiety in the synthesis of advanced fluoroquinolone antibiotics. Its value lies in enabling the production of potent antimicrobial agents with broad-spectrum activity against resistant bacterial strains. This compound is essential for R&D laboratories and manufacturers in the pharmaceutical industry focused on developing and producing next-generation antibacterial therapies.

Application

• Active Pharmaceutical Ingredient (API) Intermediate: Primary building block for the synthesis of novel fluoroquinolone antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new antibacterial agents.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and commercial API production.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory submissions.
• Veterinary Medicine: Potential application in the development of antibacterial treatments for animal health.

Basic Information

Product Name	1-Cyclopropyl-6-Fluoro-8-Methoxy-4-Oxo-7-(Piperazin-1-Yl)1,4-Dihydroquinoline-3-Carboxylic Acid
CAS No.	112811-57-1
Molecular Formula	C₁₈H₂₀FN₃O₄
Molecular Weight	361.37 g/mol
Synonyms	7-(1-Piperazinyl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinolinecarboxylic Acid; 1-Cyclopropyl-6-fluoro-8-methoxy-7-(piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid; 1-Cyclopropyl-6-fluoro-8-methoxy-7-(1-piperazinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid; Gatifloxacin Intermediate; AM-1155 Intermediate; 112811-57-1; Gatifloxacin Carboxylic Acid Derivative; 3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-6-fluoro-8-methoxy-7-(1-piperazinyl)-4-oxo-
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-6-Fluoro-8-Methoxy-4-Oxo-7-(Piperazin-1-Yl)1,4-Dihydroquinoline-3-Carboxylic Acid is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with stringent pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.