Description

H-Pyrrolo[1,2-A]Pyrimidine-3-Carboxylic Acid is a high-value heterocyclic building block and key synthetic intermediate in advanced organic chemistry. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily utilized by the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Serves as a building block for organic semiconductors, ligands for catalysis, and advanced polymers.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing fused pyrrolopyrimidine scaffolds, a privileged structure in medicinal chemistry.
• Bioconjugation & Probe Development: The carboxylic acid functionality allows for coupling to biomolecules or other moieties to create diagnostic tools or chemical probes.

Basic Information

Product Name	H-Pyrrolo[1,2-A]Pyrimidine-3-Carboxylic Acid
CAS No.	112766-33-3
Molecular Formula	C9H6N2O2
Molecular Weight	174.16 g/mol
Synonyms	Pyrrolo[1,2-a]pyrimidine-3-carboxylic acid; 3-Pyrrolo[1,2-a]pyrimidinecarboxylic acid; 1H-Pyrrolo[1,2-a]pyrimidine-3-carboxylic acid; Pyrrolo[1,2-a]pyrimidine-3-carboxylic acid (9CI); 112766-33-3 (CAS); Pyrrolopyrimidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of H-Pyrrolo[1,2-A]Pyrimidine-3-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.