Description

3-(6-Amino-1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydro-Pyrimidin-5-Yl)-3-Oxo-Propionitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular frameworks. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing next-generation compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic APIs, potentially for antiviral, anticancer, or central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the development of new pesticides or herbicides, leveraging its pyrimidine-dione core for biological activity.
• Fine Chemical Synthesis: Serves as a versatile building block for creating specialized dyes, pigments, or functional materials.
• Biochemical Research: Employed in academic and industrial R&D for studying enzyme inhibition or as a scaffold in medicinal chemistry programs.
• Nucleic Acid Analog Development: Its structural similarity to nucleobases makes it relevant for creating novel nucleotide analogs.

Basic Information

Product Name	3-(6-Amino-1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydro-Pyrimidin-5-Yl)-3-Oxo-Propionitrile
CAS No.	112735-05-4
Molecular Formula	C10H11N5O3
Molecular Weight	249.23 g/mol
Synonyms	5-Cyanoacetyl-6-amino-1,3-dimethyluracil; 6-Amino-1,3-dimethyl-5-(2-cyanoacetyl)uracil; 3-Oxo-3-(6-amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)propanenitrile; 5-(2-Cyanoacetyl)-6-amino-1,3-dimethyluracil; 6-Amino-1,3-dimethyl-5-(cyanomethylcarbonyl)uracil; 112735-05-4; 5-(2-Cyanoacetyl)amino-1,3-dimethyluracil (related isomer)
EINECS	Contact for details

Quality Control

Our 3-(6-Amino-1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydro-Pyrimidin-5-Yl)-3-Oxo-Propionitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.